Jeuveau in Chicago: Smooth Frown Lines, Fresh Expression
Jeuveau is a modern wrinkle relaxer created only for cosmetic use. It softens the frown lines between the brows and is often chosen for its quick start and natural finish. This guide explains what it is, how it compares with Botox, and what a visit looks like at any of PURE’s five Chicago-area clinics.
- As early as day 2first visible change
- Up to 4 monthsresults for many people
- About 15 minin the chair

Jeuveau at a glance
- Generic name
- PrabotulinumtoxinA
- Made by
- Evolus
- FDA approved
- 2019, frown lines
- Treatment time
- 10 to 15 minutes
- Downtime
- None for most people
- Results last
- Up to 4 months
What Is Jeuveau?
Jeuveau (pronounced “JOO-voe”) is a purified neuromodulator made by Evolus. It belongs to the same family as Botox and Dysport, but it is the first one built from the start purely for aesthetics. You will sometimes hear it called “Newtox” for that reason.
The FDA approved Jeuveau in 2019 for moderate to severe frown lines, the vertical “11s” between the eyebrows. Since then it has become a popular choice for people who want a smooth, rested look that still moves when they laugh or talk.
Want the full story? Read our complete guide to Jeuveau.
Jeuveau Before and After
Each pair shows the same person at full frown, on day 0 and day 30.




Photos courtesy of Evolus, the maker of Jeuveau. Actual Evolus clinical patients at maximum frown, not PURE Medical Spa clients. Individual results vary.
How Jeuveau Softens Frown Lines
Every time you frown or concentrate, two small muscles between the brows pull the skin together. Over years that repeated pull leaves a crease. Jeuveau quietly interrupts the nerve message that tells those muscles to tighten. The muscles rest, the skin smooths, and the crease becomes far less visible.
What the studies found
Jeuveau has been tested in five clinical trials with more than 2,100 people. In two US studies, about 7 in 10 patients had none or only mild frown lines at day 30. A separate study in Europe and Canada found that around half of patients saw some improvement by day 2.
Jeuveau and Botox, side by side
Evolus also ran a large head-to-head trial of 540 adults comparing Jeuveau with Botox Cosmetic. It found Jeuveau was not inferior, meaning it performed at least as well for frown lines at day 30. In everyday terms, both are proven options, and your injector can help you decide which suits you.
Dosing is similar too. A typical frown-line plan uses around 20 units, close to a Botox plan, so switching between the two is simple.
Your Jeuveau Results Timeline
What most people notice after treatment.
- Day 0
Treatment
A few tiny injections. Small bumps fade within the hour.
- Day 2 to 5
Early softening
Many people see the frown begin to relax in the first days.
- Day 30
Peak smoothness
Lines look their smoothest. This is when study results were measured.
- Month 3 to 4
Plan your refresh
Movement returns gradually. Book your next visit to stay smooth.
Where Our Injectors Use Jeuveau
Frown lines are the FDA-approved area. Other areas are common off-label uses your injector will discuss.
The 11s
Vertical frown lines between the brows, the approved area.
Forehead
Horizontal lines from raising your eyebrows.
Crow’s Feet
Smile lines that fan out from the outer eye.
Brow Lift
A gentle lift at the tail of the brow.
Bunny Lines
Small creases on the nose when you scrunch or laugh.
Chin Dimpling
An “orange peel” chin smoothed with tiny doses.
Who Chooses Jeuveau
Your injector will confirm at a short consultation.
Often a great match
- Adults with frown lines that show when you concentrate or frown
- First-timers who want a light, natural result
- People in their 20s and 30s thinking about prevention
- Botox clients curious to compare a similar unit dose
Talk to us first if you
- Are pregnant, breastfeeding or planning pregnancy
- Have had a reaction to any botulinum toxin product
- Have a nerve or muscle condition such as myasthenia gravis
- Have had another toxin treatment in the last 4 months
Please bring a list of your medicines and supplements. Some can affect your plan.
Jeuveau, Botox and Dysport at a Glance
| Jeuveau | Botox | Dysport | |
|---|---|---|---|
| Maker | Evolus | Allergan Aesthetics | Galderma |
| Cosmetic FDA approval | 2019 | 2002 | 2009 |
| Made for | Aesthetics only | Medical and aesthetic | Medical and aesthetic |
| Units for frown lines | About 20 | About 20 | About 50 |
| Best known for | Quick start, natural finish | Longest track record | Even spread over wide areas |
Figures are typical and vary between people. Our blog compares them further in which one lasts the longest.
Preparing and Aftercare
A few easy steps help your result settle well.
Before your visit
- Arrive with a clean face, no heavy makeup
- Tell us about any toxin treatment in the last 4 months
- Ask your doctor before pausing blood thinners; never stop them on your own
- Plan an event at least 2 weeks after treatment
After your visit
- Stay upright for about 4 hours
- Do not rub, press or massage the area today
- Save hard workouts, saunas and facials for tomorrow
- Call us if anything feels unusual
Like all botulinum toxin products, Jeuveau carries an FDA warning about the rare spread of toxin effect. Your injector will go through the full safety information with you.
Meet the Team Behind Your Jeuveau
Licensed nurse injectors and nurse practitioners, working under physician supervision.








Want Results That Last Longer? Meet Daxxify
Daxxify is a peptide-based wrinkle relaxer that can start working as early as day 1 and often lasts 4 to 6 months, compared with about 3 to 4 months for many other wrinkle relaxers. Ask your injector if it suits you.
How Jeuveau Pricing Works
Jeuveau is priced per unit, and most frown-line plans use around 20 units. Your injector shows the plan and total before treatment.
Jeuveau $8.99 per Unit
Our current Jeuveau offer. Ask your injector how many units your plan needs.
See This Month’s OffersEvolus Rewards
Jeuveau visits can earn Evolus Rewards toward future treatments.
Compare Reward ProgramsSave All Year
PURE members save on wrinkle relaxers and facials with one simple monthly plan.
Compare PlansJeuveau Near You
Every PURE clinic offers Jeuveau with the same standards. Pick the one closest to home or work.
Gold Coast
N. Dearborn St, downtown
Near River North, Streeterville, the Loop
Jeuveau in Gold Coast →Roscoe Village
North Center, Chicago
Near Lakeview, Lincoln Square, North Side
Jeuveau in Roscoe Village →Skokie
Old Orchard
Near Evanston, Wilmette, Glenview
Jeuveau in Skokie →Oak Brook
Oakbrook Terrace
Near Hinsdale, Elmhurst, Downers Grove
Jeuveau in Oak Brook →Naperville
1620 Pebblewood Ln, Ste 124
Near Aurora, Lisle, Wheaton
Jeuveau in Naperville →Jeuveau Questions, Answered
What is Jeuveau used for?
Jeuveau is FDA approved to temporarily improve moderate to severe frown lines between the eyebrows in adults. Injectors also use it off-label for forehead lines and crow’s feet.
Is Jeuveau the same as Botox?
They work in the same way and use a similar number of units, but they are different products from different makers. In a large head-to-head study, Jeuveau performed at least as well as Botox Cosmetic for frown lines.
How soon will I see results from Jeuveau?
Some people notice softening in as little as two days. Most see the full effect within one to two weeks.
How long does Jeuveau last?
Results typically last three to four months. Many people see benefit up to four months as muscle movement slowly returns.
Why is Jeuveau called Newtox?
It was the first neuromodulator developed only for cosmetic use, so it earned the nickname “Newtox” when it launched in 2019.
Will Jeuveau make me look frozen?
Not when it is dosed well. Our injectors treat only the muscles that cause your lines, so you keep natural expression.
Is Jeuveau a good choice for prevention in my 20s?
It can be. Small, well-placed doses relax the muscles that crease the skin before deep lines form. Your injector will tell you honestly if you do not need it yet.
How much does Jeuveau cost at PURE?
Jeuveau is priced per unit and your total depends on the areas treated. See our current pricing on the monthly offers page; your injector confirms the total first.
Ask a PURE Injector About Jeuveau
Not sure whether Jeuveau, Botox or Dysport is right for you? A free consultation will help you decide. Pick your nearest clinic and a time.
- Free consultation with a licensed injector
- Your plan and price confirmed before any treatment
- Open at all five PURE clinics
Prefer to talk? Call 312.312.PURE
More Reading on Jeuveau
Plain-English guides written by our injectors.
What Is Jeuveau?
A complete guide to the Newtox.
Read the guide →Jeuveau guideHow Long Does Jeuveau Last?
Tips to extend your results.
Read the guide →Jeuveau guideThe Jeuveau Process
Step by step, from consult to result.
Read the guide →Jeuveau guideJeuveau Aftercare
Keep your results looking smooth.
Read the guide →Jeuveau guideJeuveau or Dysport?
Which suits your wrinkles.
Read the guide →Jeuveau guideJeuveau for Crow’s Feet
What to know first.
Read the guide →Jeuveau guidePreventative Jeuveau
Starting early, sensibly.
Read the guide →Jeuveau guideJeuveau for Men
Planning for stronger muscles.
Read the guide →Related Treatments
Botox
The original wrinkle relaxer, with the longest track record.
Learn more →Dysport
Spreads evenly across wide areas such as the forehead.
Learn more →Facial Fillers
Restores volume in cheeks, lips and smile lines.
Learn more →Daxxify
A newer wrinkle relaxer that often lasts around six months.
Learn more →
