 
Daxxify in Chicago: Fast Results That Last Longer
Daxxify is the newest wrinkle relaxer at PURE and the only one made with a peptide formula. It can start softening frown lines as early as the next day, results often last 4 to 6 months, and many people say their skin looks brighter too. Here is how it works, how it compares with Botox, Dysport and Jeuveau, and what to expect at our five Chicago-area clinics.
- As early as day 1first visible change
- 4 to 6 monthstypical results
- Peptide formulano human or animal ingredients
Daxxify at a glance
- Generic name
- DaxibotulinumtoxinA-lanm
- FDA approved
- 2022, frown lines
- Starts working
- Day 1 to 2 for many
- Results last
- Often 4 to 6 months
- Dosing
- About 2 units per Botox unit
- Made in
- The USA
What Is Daxxify?
Daxxify (say “DAX-ih-fy”) is an FDA-approved injectable that relaxes the small muscles behind frown lines, the vertical “11s” between the eyebrows. It belongs to the same family as Botox, Dysport and Jeuveau, but its recipe is different.
Every other wrinkle relaxer is kept stable with human serum albumin, a protein taken from donated blood. Daxxify replaces it with a lab-made peptide, so it contains no human or animal-derived ingredients at all. It is also the only frown line treatment of its kind made in the United States, and it was the first new formula in this category in around two decades.
Daxxify Before and After
The same patient at full frown, before treatment and just two days later.
Photos courtesy of Revance, the maker of Daxxify. A real Daxxify patient, not a PURE Medical Spa client. Individual results vary.
Quick to Start, Slow to Fade
Two things set Daxxify apart in the treatment room: how soon it begins working and how long it keeps working.
Results as early as the next day
In clinical trial diaries, patients reported a measurable change within about two days, and some noticed softening the day after treatment. That puts Daxxify among the quickest-starting wrinkle relaxers we offer, and it often settles in sooner than Jeuveau, which many people first notice around day two to five.
Results that often last 4 to 6 months
Botox and Dysport usually hold for three to four months. Daxxify tends to go further. Four weeks after treatment, about three in four trial patients had improved by at least two grades on the frown line scale, and more than half still had no or only minor frown lines six months later. The result then fades gradually rather than all at once.
For you, that can mean two visits a year instead of three or four. Your own timeline depends on your muscle strength, metabolism and activity level, and your injector will tell you what to expect.
The Peptide Difference, and the Glow
A peptide is a short chain of amino acids, the building blocks of protein. In Daxxify, the peptide surrounds the active ingredient and helps it attach firmly where it is needed, then stay ready to work over time. Researchers believe this is a big part of why results tend to last longer.
Smoother, brighter-looking skin
Many people notice more than softer lines. In a small survey of Daxxify patients, close to nine in ten said their skin looked radiant or bright afterward, and almost all agreed the skin between their brows looked smooth. Our clients often describe the result as a fresh, healthy glow rather than a “done” look.
Your Daxxify Results Timeline
What most people notice after treatment.
- Day 1 to 2
Early softening
Many people see the frown start to relax within a day or two.
- Week 2
Settled result
Lines look smooth and skin looks fresh. Ideal for a photo check.
- Week 4
Peak improvement
When trial patients showed their strongest change.
- Month 4 to 6
Plan your refresh
Movement returns slowly. Book again when you see it.
Where Our Injectors Use Daxxify
Frown lines are the FDA-approved area. Other areas are common off-label uses your injector will discuss with you.
The 11s
Vertical frown lines between the brows, the approved area.
Forehead
Horizontal lines that form when you raise your eyebrows.
Crow’s Feet
Smile lines that fan out from the outer corner of the eye.
Brow Lift
A gentle lift at the tail of the brow for a more open look.
Bunny Lines
Small creases on the nose when you scrunch or laugh.
Chin Dimpling
An “orange peel” chin smoothed with small doses.
Who Chooses Daxxify
Your injector will confirm at a free consultation.
Often a great match
- Adults with frown lines that show when you concentrate
- Busy people who would like fewer visits each year
- Tox clients whose results seem to fade quickly
- Anyone who prefers a formula with no human or animal ingredients
Talk to us first if you
- Are pregnant, breastfeeding or planning pregnancy
- Have had a reaction to any botulinum toxin product
- Have a nerve or muscle condition such as myasthenia gravis
- Have had another toxin treatment in the last 3 months
Please bring a list of your medicines and supplements. Some can affect your plan.
Daxxify Units Explained
Units are specific to each brand, so a unit of Daxxify is not the same as a unit of Botox. As a simple guide, a Daxxify plan uses about two units for every one unit of Botox for the same area. That is normal and does not mean you are getting a stronger or weaker treatment.
To keep comparisons easy, PURE prices Daxxify per Botox-equivalent unit. If you know how many Botox units you usually have, your injector can show you the matching Daxxify plan and total before anything is done.
Daxxify, Botox, Dysport and Jeuveau at a Glance
| Daxxify | Botox | Dysport | Jeuveau | |
|---|---|---|---|---|
| Cosmetic FDA approval | 2022 | 2002 | 2009 | 2019 |
| Stabilizer | Peptide, no albumin | Human albumin | Human albumin | Human albumin |
| First visible change | As early as day 1 | Around day 3 to 5 | Around day 2 to 3 | Around day 2 to 5 |
| Typical results | 4 to 6 months | 3 to 4 months | 3 to 4 months | 3 to 4 months |
| Units vs Botox | About 2 to 1 | 1 to 1 | About 2.5 to 1 | About 1 to 1 |
Figures are typical and vary between people. Read more about which wrinkle relaxer lasts the longest.
Recognized by Beauty Editors
Daxxify has picked up several well-known awards since launch, including a Cosmopolitan Holy Grail Beauty Award, a Shape Skin Award for long-lasting results, and a spot on TIME’s Best Inventions list.
Preparing and Aftercare
A few easy steps help your result settle well.
Before your visit
- Arrive with a clean face, no heavy makeup
- Tell us about any toxin treatment in the last 3 months
- Ask your doctor before pausing blood thinners; never stop them on your own
- Plan an event at least 1 to 2 weeks after treatment
After your visit
- Stay upright for about 4 hours
- Do not rub, press or massage the area today
- Save hard workouts, saunas and facials for tomorrow
- Call us if anything feels unusual
Like all botulinum toxin products, Daxxify carries an FDA warning about the rare spread of toxin effect. Your injector will go through the full safety information with you.
Meet the Team Behind Your Daxxify
Licensed nurse injectors and nurse practitioners, working under physician supervision.
How Daxxify Pricing Works
Daxxify uses about 2 units for every 1 Botox unit, so PURE prices it per Botox-equivalent unit to keep comparisons simple. Your injector confirms your plan and total before treatment.
Daxxify $12.99 per Botox-Equivalent Unit
Daxxify uses about 2 units for every 1 Botox unit, so this price covers 2 Daxxify units. Your injector confirms your plan and total first.
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Compare PlansDaxxify Near You
Every PURE clinic offers Daxxify with the same standards. Pick the one closest to home or work.
Gold Coast
N. Dearborn St, downtown
Near River North, Streeterville, the Loop
Daxxify in Gold Coast →Roscoe Village
North Center, Chicago
Near Lakeview, Lincoln Square, North Side
Daxxify in Roscoe Village →Skokie
Old Orchard
Near Evanston, Wilmette, Glenview
Daxxify in Skokie →Oak Brook
Oakbrook Terrace
Near Hinsdale, Elmhurst, Downers Grove
Daxxify in Oak Brook →Naperville
1620 Pebblewood Ln, Ste 124
Near Aurora, Lisle, Wheaton
Daxxify in Naperville →Daxxify Questions, Answered
What is Daxxify used for?
Daxxify is FDA approved to temporarily improve moderate to severe frown lines between the eyebrows in adults. Injectors may also use it off-label for forehead lines and crow’s feet.
How fast does Daxxify work?
Some people notice softening the day after treatment, and most see a measurable change within about two days. That is one of the quickest starts of any wrinkle relaxer.
How long does Daxxify last?
Results often last 4 to 6 months, compared with 3 to 4 months for Botox and Dysport. In trials, more than half of patients still had no or minor frown lines at six months.
Does Daxxify make your skin glow?
Many people say so. In a small patient survey, close to nine in ten rated their skin as radiant or bright after treatment.
Why does Daxxify use more units than Botox?
Units are unique to each brand. Daxxify uses about two units for every one Botox unit, which is why PURE prices it per Botox-equivalent unit.
Does Daxxify contain human or animal ingredients?
No. It is stabilized with a peptide instead of human serum albumin and has no human or animal-derived components.
Can I switch to Daxxify from Botox, Dysport or Jeuveau?
Yes. Your injector will usually suggest waiting until your current tox has worn off, then build a Daxxify plan matched to your usual dose.
How much does Daxxify cost at PURE?
Daxxify is priced per Botox-equivalent unit, and your total depends on the areas treated. See the current price in the offers section on this page or on our monthly offers page.
Ask a PURE Injector About Daxxify
Wondering whether Daxxify or your usual tox is the better fit? A free consultation will help you decide. Pick your nearest clinic and a time.
- Free consultation with a licensed injector
- Your plan and price confirmed before any treatment
- Open at all five PURE clinics
Prefer to talk? Call 312.312.PURE
More Reading on Daxxify
Plain-English guides written by our injectors.
Which Tox Lasts the Longest?
How the brands compare on staying power.
Read the guide →Daxxify guideInjectable Brands
The 2026 guide to approved tox and fillers.
Read the guide →Daxxify guideXeomin for Frown Lines
Another option, and who may prefer it.
Read the guide →Daxxify guideFrown Lines at Rest
What helps lines that stay when you relax.
Read the guide →Daxxify guideYour Brow Position Matters
How it shapes any tox plan.
Read the guide →Daxxify guideTox and Eyebrow Movement
Can it change your expressions?
Read the guide →Daxxify guideTox for Men
Why men often need a different plan.
Read the guide →Daxxify guideComparing Tox Costs
Value beyond the price per unit.
Read the guide →