 
Microneedling is a favorite for smoother texture, softer acne scars and finer lines. If you have been offered Ariessence as an add on, you may be wondering whether it is worth it.
Ariessence contains platelet derived growth factor (PDGF), a protein involved in the skin’s normal repair process. It is applied to the skin after certain procedures. Early research is encouraging, but adding PDGF does not guarantee better results for everyone. Learn more about Ariessence at PURE and microneedling at PURE.
Key Takeaways
- ✓Ariessence is a topical PDGF product applied after microneedling, not an injectable.
- ✓A small study with RF microneedling showed promising results; larger studies are still needed.
- ✓No blood draw is needed, unlike PRP.
- ✓Microneedling alone may be enough for some skin goals.
What Is Ariessence PDGF Treatment?
Ariessence uses laboratory made PDGF-BB combined with hyaluronic acid. It is applied to the skin after a procedure such as microneedling. It is not a filler and it is not a prescription wound healing medicine. Our overview of what Ariessence is covers the basics.
How It Differs From PRP
Platelet rich plasma (PRP) comes from your own blood, and microneedling with PRP is often called a vampire facial. Ariessence needs no blood draw. They are different products, so the results of one cannot be assumed for the other. Read microneedling with PRP for that comparison.
How Does Professional Microneedling Work?
Professional microneedling uses fine needles to create tiny channels in the skin. This starts a natural repair response that can improve the look of scars, texture and fine lines over a series of visits. The channels close quickly as the skin heals.
Microneedling can help with mild sun damage, but deeper discoloration or scarring may need another approach, such as a chemical peel or laser, after a skin assessment. Our microneedling recovery guide shows what the days afterward look like.
Ariessence vs Microneedling: What Does the Evidence Say?
A small published trial compared RF microneedling followed by topical PDGF with RF microneedling followed by a standard ointment. It involved 12 people over 30 days. The PDGF side scored better on several skin imaging measures, patients reported a better recovery experience and no serious side effects were reported.
Reading the Research Honestly
The trial was small and short, it used RF microneedling rather than standard microneedling and some investigators had ties to the manufacturer. It does not prove that every patient will benefit or that results last long term. Strong research comparing Ariessence with ordinary microneedling alone is still limited.
| Option | What it involves | Good to know |
|---|---|---|
| Microneedling alone | Fine needles create micro channels; skin repairs itself | Proven, simpler and often enough for mild texture concerns |
| Microneedling plus Ariessence | Topical PDGF applied right after microneedling | May support recovery and glow; evidence still developing |
| RF microneedling plus PDGF | Needles plus radiofrequency heat, then topical PDGF | Where the small trial was done; RF has its own risks |
| Microneedling plus PRP | Your own platelets applied after treatment | Needs a blood draw; different product and evidence |
PURE MEDICAL SPA CHICAGO
Smoother, Brighter Skin Starts Here
Ask our team whether Ariessence suits your microneedling plan.
Possible Benefits of Adding PDGF
People choose PDGF growth factor microneedling for extra support after treatment. Possible benefits include:
- ✓Smoother looking texture
- ✓A brighter overall skin appearance
- ✓A more comfortable recovery for some patients
- ✓Less noticeable redness for some patients
- ✓No blood draw
These are possible results, not promises. Ariessence is not proven to repair every scar, remove deep wrinkles or replace regular skincare. Read Ariessence for acne scars and how many Ariessence sessions you need for more detail.
Is RF Microneedling With PDGF Different?
Yes. Standard microneedling makes tiny channels. RF microneedling also delivers radiofrequency heat below the surface before topical PDGF is applied. RF devices carry their own risks, including burns, scarring, unwanted fat loss and nerve injury, and PDGF does not remove those risks. The FDA has also noted that microneedling devices are not cleared to deliver cosmetics into the skin. Compare the two in microneedling vs RF microneedling.
Who Should Consider This Treatment?
People with uneven texture, mild wrinkles or acne scars often ask about this option. If you have sensitive skin, active acne or a skin infection, you may need a different plan or time to heal first. If you have facial moles, read microneedling around moles.
When Microneedling Alone Is Enough
Someone with mild texture changes may prefer a simpler plan, while deeper scars often need a series of visits whichever option you choose. Your provider should explain realistic results and costs before suggesting an add on.
Ariessence at PURE Medical Spa
At PURE Medical Spa, Ariessence is offered as a topical add on to selected skin treatments. During your visit, your provider reviews your skin concerns and treatment history, explains the current evidence and helps you decide whether microneedling alone or microneedling with PDGF fits your goals and budget. There is never pressure to add extra treatment. If you are also weighing fillers, see Sculptra after dissolving filler.
Visit PURE Medical Spa Across Chicagoland
PURE Medical Spa welcomes you at five convenient clinics in Chicago and the suburbs. Ask our team which location offers microneedling and Ariessence and pick the visit that fits your schedule.
PURE Medical Spa Gold Coast (N. Dearborn), Chicago
875 N Dearborn St, Suite 300, Chicago, IL 60610
Book OnlineCall or Text 312.312.7873Naperville 331.283.0440
Frequently Asked Questions
Does Ariessence PDGF improve microneedling results?
Early research suggests it may improve skin appearance after RF microneedling, but larger studies are needed.
Is microneedling with PDGF better than microneedling alone?
Not for everyone. One small RF study showed promising results, but it cannot answer that question for all devices and skin types.
What are the benefits of adding Ariessence to microneedling?
Possible benefits include smoother looking skin and a more comfortable recovery. Results differ between patients.
Can Ariessence reduce redness after microneedling?
It might help some people, but research has not established a reliable reduction in redness or recovery time.
Is Ariessence PDGF worth adding to microneedling treatment?
Consider your skin goals, budget and your provider’s advice. It is optional, and microneedling alone may be the right choice.
BOOK YOUR VISIT
Your Smoothest Skin, Your Way
Book a microneedling consultation at a PURE clinic near you.
Safety note: Microneedling is not suitable for everyone, including people with some active skin infections, bleeding conditions or poor wound healing. Contact a medical professional for increasing pain, spreading redness, fever or pus after treatment. Ariessence is intended for topical cosmetic use only, not injection. This article is educational and does not replace a medical assessment.
References
- U.S. Food and Drug Administration: Microneedling devices
- National Library of Medicine: Topical PDGF after RF microneedling, randomized trial
