 
Mature skin changes in ways many people notice around 50 and beyond: more fine lines, less bounce, a duller surface and slower recovery after treatments. Ariessence is a topical PDGF product applied after procedures such as microneedling, and it has drawn interest as a way to support that recovery. Here is how Ariessence for mature skin works, what the research says and what to expect at PURE.
Learn more about Ariessence at PURE and microneedling at PURE.
Key Takeaways
- ✓Ariessence combines recombinant PDGF with hyaluronic acid.
- ✓It is applied on the skin after a procedure, not injected.
- ✓No blood draw is needed, unlike PRP.
- ✓It is a cosmetic product, not an FDA approved drug, and results vary.
Why Does Mature Skin Change Over Time?
With age, the skin makes less collagen and elastin, cell turnover slows and the surface holds less moisture. Years of sun exposure add rough texture and uneven tone. Hormone changes around menopause can speed some of this up. These shifts are why mature skin can take longer to recover after resurfacing treatments.
What Mature Skin Often Needs
Mature skin usually responds well to gentle, steady care: hydration, sun protection and treatments that support repair rather than strip the surface.
What Is PDGF Skin Treatment?
PDGF stands for platelet derived growth factor, a signaling protein involved in the body’s natural wound healing. Ariessence uses a recombinant form made in a lab, paired with hyaluronic acid, and is applied to the skin right after a treatment that opens tiny channels.
How PDGF Supports Skin Rejuvenation
The scientific interest in PDGF comes from its role in tissue repair, where it helps signal cells involved in rebuilding. Applied after microneedling, the aim is to support the skin’s own recovery response. Read Ariessence PDGF treatment for youthful, radiant skin.
What the Research Shows
A 2025 randomized controlled trial in the Journal of Cosmetic Dermatology studied topical PDGF after RF microneedling and reported improvements in recovery and skin appearance. It is one trial, and more independent studies would help confirm the results.
Potential Benefits of Ariessence for Mature Skin
When it suits your skin, Ariessence may offer:
- ✓Support for the post procedure recovery process
- ✓A smoother looking skin texture over time
- ✓A complement to professional skin procedures
- ✓Hydration from hyaluronic acid
- ✓An option without a blood draw
Who May Consider This Skin Rejuvenation Treatment?
Ariessence may be discussed for adults who want fresher looking skin, plan microneedling and want extra recovery support, or prefer not to have blood drawn for PRP. It may suit people who notice fine lines, dull tone or crepey texture. Compare microneedling with PRP and Ariessence vs microneedling.
PURE MEDICAL SPA CHICAGO
Fresher, Healthier Looking Skin at Any Age
Ask our team whether Ariessence fits your skin plan.
Ariessence After Microneedling: What Should You Expect?
Your provider performs microneedling, then applies Ariessence to the treated skin. Mild redness and tightness are common for a day or two. See microneedling recovery day by day.
Aftercare Steps
During recovery, it helps to:
- ✓Follow your provider’s cleansing and moisturizing instructions
- ✓Avoid exfoliating acids and retinoids until cleared
- ✓Apply broad spectrum sunscreen as directed
- ✓Avoid picking, scratching or rubbing the area
- ✓Stay hydrated and eat balanced meals
There is no universal follow up schedule for everyone. Our guide to skincare after microneedling has more tips.
Ariessence vs Traditional Skin Boosters
Injectable skin boosters such as SKINVIVE place hyaluronic acid into the skin for hydration and glow. Ariessence is topical and is used to support recovery after a procedure.
| Feature | Ariessence | Injectable skin booster | PRP with microneedling |
|---|---|---|---|
| How it is used | Applied on the skin after a procedure | Injected into the skin | Your own platelets applied or injected |
| Main ingredients | Recombinant PDGF and hyaluronic acid | Hyaluronic acid | Concentrated platelets from your blood |
| Blood draw | No | No | Yes |
| Main goal | Recovery support and skin quality | Hydration and smoothness | Recovery support and skin quality |
Treatment Monitoring, Nutrition and Recovery
Good habits help any skin plan:
- ✓Drink enough water through the day
- ✓Use SPF 30 or higher and limit strong sun
- ✓Keep a gentle cleansing and moisturizing routine
- ✓Compare photos taken in similar lighting
Pairing With Other Mature Skin Treatments
Some plans also include laser resurfacing for mature skin, dermal fillers for mature skin or Botox after 50. You can also compare microneedling vs RF microneedling and SKINVIVE vs microneedling.
Ariessence Cost: What Influences Pricing?
Your price depends on the procedure it is paired with, the treatment area, the number of sessions and any current offers. Your provider confirms the full cost at your consultation.
How PURE Plans Ariessence for Mature Skin
At PURE Medical Spa, your provider looks at your skin, history, sun damage and recovery time, then explains whether microneedling with Ariessence is a sensible step. Treatment is tailored to mature skin, with settings and spacing chosen for comfort and healing.
Visit PURE Medical Spa Across Chicagoland
PURE Medical Spa welcomes you at five convenient clinics in Chicago and the suburbs. Every PURE clinic offers Ariessence, so you can pick the location and visit time that fit your schedule.
PURE Medical Spa Gold Coast (N. Dearborn), Chicago
875 N Dearborn St, Suite 300, Chicago, IL 60610
Book OnlineCall or Text 312.312.7873Naperville 331.283.0440
Frequently Asked Questions
Is Ariessence for mature skin a good option?
It may be, especially when paired with microneedling. Your provider reviews your skin and goals first, and results vary between people.
What is PDGF skin treatment?
It uses platelet derived growth factor, a protein involved in natural healing. Ariessence uses a lab made form with hyaluronic acid.
How does PDGF support skin rejuvenation?
PDGF is involved in tissue repair signals. Applied after microneedling, it aims to support the skin’s own recovery.
Can Ariessence be used after microneedling?
Yes. That is its main use, applied to the skin right after the procedure.
Is Ariessence better than traditional skin boosters?
They do different jobs. Skin boosters are injected for hydration, while Ariessence is topical support after a procedure.
BOOK YOUR VISIT
Give Mature Skin the Care It Deserves
Book an Ariessence consultation at a PURE clinic near you.
Safety note: Ariessence and microneedling may not suit everyone. Avoid treatment over active infection, open wounds, active acne flares or severely irritated skin. Tell your provider about pregnancy, skin conditions, allergies and medicines. Contact a clinician for increasing pain, spreading redness, swelling, pus or fever after treatment. This article is educational and does not replace a medical assessment.
References
- National Institute on Aging: Skin care and aging
- National Library of Medicine: Microneedling, StatPearls
