Thinking about platelet-rich fibrin (PRF) this year? This plain-English guide explains what PRF costs in 2025, why prices vary, and how Chicago-specific updates may affect your quote. It also links to trusted medical sources and related learning so you can book with confidence.
What PRF is (and why people choose it)
PRF is made from your own blood samples. A clinician draws a small tube, centrifuged to separate the red blood cells from a fibrin matrix rich in platelets and white cells. PRF releases growth factors slowly in the targeted area, which may support collagen and tissue repair with a natural approach.
Early studies in facial aesthetics report improved fine lines and improved skin texture, including around the eye area. Evidence remains modest but promising, with favorable safety when performed by trained medical professionals.
2025 Chicago price ranges (typical, before promos)
Prices vary by provider, injector credentials, and treatment plan. In Chicago and nearby suburbs, these are common ranges we see in 2025:
- PRF under eyes (eye hollows/tear trough support): $600–$1,200 per session
- Full-face PRF (injections or PRF-EZ gel): $800–$1,800 per session
- PRF for acne scars (spot or region-focused): $500–$1,200 per session
- PRF hair injections (nonsurgical): $600–$1,200 per session; most plans bundle 3–4 sessions
Most patients need a series of 2–4 sessions spaced 4–6 weeks apart, then maintenance every 6–12 months based on results and goals.
These figures reflect prevailing 2025 rates across large Midwest metros and public price lists, plus our ongoing market scan. Actual quotes depend on assessment, injector expertise, and whether you combine dermal fillers or devices in the same visit.
Why prices differ
- Treatment scope: One small injection site costs less than full-face or hairline coverage.
- Provider credentials: MD/DO or APRN-led services often price higher due to expertise.
- Technique and materials: Classic liquid i-PRF vs PRF-EZ gel; microneedling add-ons; topical vs injectable.
- Clinic costs: City location, staffing, and compliance requirements affect fees.
- Package savings: Bundles lower per-session cost compared with single visits.
Chicago-specific factors in 2025
Chicago’s minimum wage increased on July 1, 2025. Rising labor costs may influence aesthetic pricing across the city this year.
PRF vs PRP: does PRF cost more?
Often, yes—slightly. PRF spins at lower speeds without anticoagulants, creating a fibrin network that can release growth factors in a slower, sustained way. This processing and training may add to cost, but many practices still price PRF close to PRP.
Safety, who can treat you, and Illinois rules
Illinois treats injectable aesthetic procedures as the practice of medicine. Treatments must be performed by, or delegated and supervised by, a licensed medical professional within a valid physician-patient relationship. This protects you and should be part of your price discussion.
Common, short-term effects include redness, swelling, and bruising at the injection site. Because PRF uses the body’s natural healing components, allergic reactions are rare, though any injection carries risks. Discuss medicines, including blood thinners, with your provider.
How to budget (simple planner)
Most under-eye or small-area plans: 2–3 sessions
- Example: $800 × 3 = $2,400 this year; maintenance next year may be 1 session.
Full-face rejuvenation plans: 3–4 sessions
- Example: $1,200 × 3 = $3,600; adding microneedling can add $200–$400 per visit.
Hair restoration plans: 3–4 sessions + periodic boosters
- Example: $900 × 4 = $3,600; boosters $600–$900 as needed.
Ask about bundles, membership, or 0% APR medical financing to smooth costs.
Evidence corner: why mechanism matters for value
Laboratory and clinical work suggest PRF provides higher cumulative growth factor release than PRP, with slower, prolonged delivery that may support soft-tissue healing. This mechanistic edge helps explain why some patients accept slightly higher PRF treatment cost versus PRP.
Small aesthetic studies report under-eye texture and brightness gains after PRF, though data sets are still limited. Expect gradual change over weeks as tissue remodels, not an instant “filler” effect.
PRF supports skin rejuvenation by forming a fibrin matrix from your own blood components. This scaffold releases growth signals that guide skin cell repair and nourish nearby blood vessels, which supports natural healing processes. Recovery time is usually short, but the plan and any side effect risks vary depending on skin conditions and medical conditions. Your clinician will screen for factors that raise the risk of blood clots and will review medicines that affect clotting.
Treatment plans match your aesthetic goals and overall health. Many patients choose PRF alone, while others combine treatment options such as gentle laser resurfacing for texture and signs of aging. A study showed improvement after a series of sessions, so clear expectations matter. Ongoing clinical trials continue to refine dosing and methods.
Ask about the number of sessions, expected recovery time, and when results peak. This informed approach helps you balance value, safety, durability overall.
Insurance and HSA/FSA
PRF for cosmetic use is not insurance-covered. Many patients use HSA/FSA when allowed by plan rules. Keep itemized receipts and a treatment plan from your provider.
FAQs
How much is PRF under eyes in Chicago?
Typical quotes are $600–$1,200 per session. Most plans include 2–3 sessions for the eye area.
Is PRF safe and effective?
When delivered by qualified clinicians under Illinois rules, PRF has a solid safety profile and minimal risks; outcomes vary.
PRF, PRP, or filler—how do I choose?
PRF uses your own biology and builds results slowly. Platelet rich plasma (PRP) is similar but releases growth factors faster. Dermal fillers give instant volume but are synthetic. Many plans combine options based on goals.
How many sessions will I need?
Most patients plan 2–4 sessions, then maintenance every 6–12 months.