When it comes to refreshing your appearance, two of the most popular treatment options are dermal fillers and PRF. Patients often ask: Is PRF better than fillers? The truth is, both treatments can deliver incredible results, but they work in very different ways. Understanding the unique benefits of each will help you choose the best option for your goals.
At Pure Medical Spa, we offer both PRF treatment and filler injections, giving patients customized plans designed to achieve natural, youthful results. This guide will break down the science behind PRF and fillers, their differences, and how to decide which treatment may be right for you.
What Is PRF?
PRF, or platelet rich fibrin, is a natural concentrate made from your patient’s own blood. A small sample is drawn and spun in a centrifuge through a special PRF procedure. Unlike platelet rich plasma (PRP), PRF is spun at a lower speed, which preserves white blood cells, stem cells, and platelets within a fibrin matrix.
When delivered through PRF injections, the serum releases growth factors gradually, triggering collagen and elastin production. This process improves PRF skin elasticity, reduces wrinkles, and delivers a gradual lift. Because it relies on your own biology, PRF carries minimal risk and provides PRF anti-aging benefits that look subtle and natural.
(Reference: NIH – Platelet concentrates in regenerative medicine)
What Are Fillers?
Dermal fillers are a popular cosmetic procedure used to restore volume and smooth deep lines. The most common type, hyaluronic acid fillers, works by adding immediate plumpness under the skin. Fillers are ideal for contouring cheeks, enhancing lips, and smoothing folds around the mouth.
Fillers for wrinkles deliver fast results, but they don’t address the underlying cause of aging. Unlike PRF, they don’t stimulate collagen or repair tissue—they simply fill hollow areas. Over time, fillers dissolve and need to be repeated.
PRF vs Fillers: Key Differences
So, Is PRF better than fillers? It depends on what you’re hoping to achieve. Let’s look at the main differences:
- PRF treatment: Derived from your patient’s own blood, focuses on stimulating collagen and natural repair. Best for subtle, long-lasting improvements.
- Dermal fillers: Synthetic gels that provide instant volume. Best for contouring and correcting deep folds.
PRF anti-aging benefits include gradual natural skin tightening, improvement in fine lines, and overall healthier skin. Fillers are ideal when patients want immediate, visible results. Many choose to combine both for optimizing results.
PRF for Skin Rejuvenation
Patients often ask how PRF can specifically improve the skin. Some common uses include:
- PRF for skin rejuvenation: Restores hydration, glow, and elasticity.
- PRF for wrinkles: Reduces fine lines and creases.
- PRF for fine lines: Softens subtle signs of aging.
- PRF for sagging skin: Improves firmness by repairing deeper tissues.
- PRF under eyes and PRF for dark circles: Reduces hollows, puffiness, and discoloration.
- PRF facial rejuvenation: Enhances skin tone and texture for overall radiance.
Because PRF relies on platelet derived growth factor and other natural healing molecules, results look subtle yet powerful.
(Reference: PubMed – Clinical applications of PRF in tissue regeneration)
How Long Does PRF Last vs Fillers?
One of the most important differences is longevity.
- How long does PRF last? Typically, 12–18 months, thanks to the gradual release of growth factors that continue healing over time. PRF longevity can be extended with maintenance.
- Fillers: Depending on the type, results last 6–12 months before dissolving.
This difference is why many patients at Pure Medical Spa ask, “Is PRF better than fillers?” For natural skin repair, PRF often provides longer-lasting results. For immediate contouring, fillers may be the better choice.
PRF vs PRP: Why PRF Is Unique
Many patients are familiar with PRP, but wonder how it compares. In PRF vs PRP:
- PRP is spun at high speeds, which separates platelets but loses some healing cells.
- PRF is spun slower, creating a fibrin mesh with higher cell counts and more growth factors.
As a result, PRF delivers stronger PRF anti-aging benefits and is increasingly preferred for facial rejuvenation.
PRF Results Before and After
Patients love seeing PRF results before and after their treatments. Improvements often include:
- Softer fine lines and wrinkles.
- Brighter, smoother under-eye area.
- More even skin tone and texture.
- Noticeable natural skin tightening.
Because PRF works at the cellular level, results continue to improve for weeks after treatment. Unlike fillers, which show immediate volume but fade, PRF builds lasting changes.
(Reference: U.S. National Library of Medicine – Advances in PRF therapy)
Cost: PRF vs Fillers
When comparing PRF cost to fillers, PRF is often slightly higher upfront because of the advanced PRF procedure. However, because PRF longevity can outlast fillers, many patients find it more cost-effective over time.
At Pure Medical Spa, we provide personalized care plans, flexible pricing, and the opportunity to schedule a consultation to discuss your goals and budget.
Who Should Choose PRF and Who Should Choose Fillers?
- Choose PRF treatment if you want natural, subtle, and long-term improvements in skin condition through stimulating collagen.
- Choose dermal fillers if you want fast volume correction, sharper facial contours, or an event-ready refresh.
- Combine both for patients who want immediate lift with lasting repair.
The best choice depends on your goals, and at Pure Medical Spa, our experts guide you through all treatment options for optimizing results.
Why Choose Pure Medical Spa for PRF and Fillers?
At Pure Medical Spa, we specialize in both PRF injections and filler injections. Patients trust us because we provide:
- Expert injectors trained in regenerative and cosmetic treatments.
- Safe, FDA-cleared protocols for PRF and fillers.
- Personalized plans for PRF under eyes, PRF for wrinkles, PRF facial rejuvenation, and more.
- Affordable pricing with financing options.
✨ Ready to learn Is PRF better than fillers?
Call/Text 312.312.7873 or Book Online today.
Final Thoughts
So, Is PRF better than fillers? The answer depends on your goals. For instant lift and contour, fillers are excellent. For natural, long-term improvements in elasticity, tone, and PRF anti-aging benefits, PRF stands out. Many patients combine both treatments for the best of both worlds.
At Pure Medical Spa, we believe your beauty journey should be personalized. Whether you choose PRF, fillers, or both, our experts ensure safe, natural, and lasting results.