When it comes to smoothing fine lines and wrinkles, two popular injectable options come to mind: Xeomin and Botox. But what happens when you combine them? Is it safe, more effective, or just hype?
At Pure Medical Spa, clients often ask about using Botox and Xeomin together. In this guide, we’ll break down the science, the benefits, the results, and whether combining Xeomin and Botox can truly give you the best of both worlds.
What Is the Difference Between Xeomin and Botox?
Both Xeomin and Botox are FDA-approved neurotoxins derived from botulinum toxin type A. They work by temporarily relaxing targeted muscles to reduce the appearance of dynamic wrinkles like crow’s feet, forehead lines, and frown lines.
The biggest distinction?
Xeomin is a “naked” neurotoxin — it contains no accessory proteins. That means it’s less likely to cause resistance in the body, which can sometimes happen with Botox over time. If you’re looking for a Botox alternative, Xeomin is often the top recommendation.
Why Consider Botox and Xeomin Together?
Can you use Botox and Xeomin at the same time?
Yes — and many advanced injectors at Pure Medical Spa strategically use Botox and Xeomin together for a more tailored outcome.
Here’s why it works:
- Different muscles, different needs: Some facial muscles may respond better to one product over the other.
- Reduced tolerance: By alternating products, the body is less likely to build resistance.
- Customized longevity: Xeomin may last longer in some areas; Botox may act quicker in others.
So, combining Xeomin and Botox best neurotoxin for wrinkles “can offer enhanced precision, balanced results, and greater longevity.
Xeomin vs Botox Results: What Should You Expect?
One of the most common questions we hear is: “Xeomin vs Botox results – which is better?”
At Pure Medical Spa, we emphasize that results vary from person to person. Here’s a breakdown:
- Botox: Results typically appear in 3–5 days, lasting 3–4 months.
- Xeomin: Results may appear in 3–7 days, and some patients report effects lasting up to 5 months.
Clients often find Xeomin for forehead wrinkles especially effective when they’ve plateaued with Botox. For others, Botox remains the go-to.
Our experienced injectors will determine the right approach, sometimes recommending Xeomin treatment before and after Botox to improve outcomes over time.
Who Should Consider Xeomin and Botox?
Whether you’re searching for “botox close to me”, or exploring botox fillers near me, it’s important to know your options.
You may benefit from Xeomin and Botox if you:
- Want natural-looking wrinkle reduction
- Are experiencing diminishing results from one neurotoxin
- Are looking for face slimming Botox near me
- Have moderate to severe dynamic wrinkles
- Prefer a customized treatment plan with minimal downtime
And if you’re looking for the best Botox doctor near me, our medical providers at Pure Medical Spa are highly trained in both Xeomin and Botox injections.
What Not to Do After Botox or Xeomin
After your appointment, it’s important to follow proper aftercare to ensure results last.
Here’s what not to do after Botox or Xeomin:
- Don’t lie down or bend over for 4 hours
- Avoid vigorous exercise for 24 hours
- Skip facials or massages on the treated area for at least a week
- Don’t apply pressure to the area
- Avoid alcohol and blood thinners the day of and after your treatment
Wondering “can you get a facial after Botox?” It’s best to wait at least 5–7 days. Our providers will guide you on when it’s safe to schedule your next facial after Botox.
Xeomin vs Botox for Frown Lines and Forehead Wrinkles
When it comes to Botox vs Xeomin for frown lines, both work beautifully. But again, some patients notice less “freezing” with Xeomin and more natural expression.
In terms of Xeomin vs Botox for forehead wrinkles, the difference often lies in how your facial muscles react and how long the product lasts.
Every face is different — that’s why consultations at Pure Medical Spa are so crucial.
How Long Does Xeomin Last?
One of the top questions we get: How long does Xeomin last?
While Botox usually lasts around 3–4 months, Xeomin can last up to 5 months in some patients, depending on metabolism, injection site, and lifestyle factors.
That said, results are very similar, and many patients alternate between the two for the best effect.
The Natural Botox Look with Xeomin
A major trend in aesthetics is achieving a “Botox natural” look. Patients aren’t looking for that frozen look — they just want to look refreshed.
Xeomin’s formula, free of accessory proteins, often produces a softer appearance. This makes it perfect for first-timers or those looking for subtle enhancement.
So whether you’re searching “botox or xeomin” online or exploring botox clinics near me, Pure Medical Spa delivers results that look natural, never overdone.
Booking Your Appointment at Pure Medical Spa
Ready to see what combining Xeomin and Botox can do for your skin?
At Pure Medical Spa, we specialize in customized facial injectables, using only FDA-approved products. Whether you’re trying Xeomin for the first time or you’re a seasoned Botox user, we’ll create a personalized plan to help you look refreshed, natural, and youthful.
Book Your Appointment:
Call/Text: 312.312.7873
Let our expert providers guide you toward the most effective treatment — whether that’s Botox, Xeomin, or Botox and Xeomin together.
Frequently Asked Questions
✅ Can you use Botox and Xeomin at the same time?
Yes. Many aesthetic experts now recommend using Botox and Xeomin together for personalized results. They target different muscle groups and help prevent resistance over time.
✅ Which is stronger: Xeomin or Botox?
They’re equally effective, but some patients report longer-lasting results with Xeomin due to its purified formula. Others prefer Botox for faster onset.
✅ Xeomin vs Dysport vs Botox: What’s the difference?
- Botox: Most well-known brand, fast onset.
- Xeomin: No additives, reduced risk of resistance.
- Dysport: Spreads more easily; great for large areas like the forehead.
✅ Xeomin vs Botox duration — which lasts longer?
On average, Xeomin may last slightly longer, but individual results vary.
✅ What to expect after Xeomin injections?
Mild redness or swelling at injection sites is normal. You can resume most activities immediately. Full results appear within 3–7 days and can last up to 5 months.
Final Thoughts: Is Combining Xeomin and Botox Right for You?
There’s no one-size-fits-all answer in aesthetics. But if you’re searching for “botox places near me” or “botox clinics” that offer advanced, personalized care, Pure Medical Spa is here to guide you.
Botox and Xeomin together can deliver exceptional results — more natural, more customized, and longer-lasting. Schedule your consultation and experience the next level of injectable artistry.